| Handheld Raman spectroscopy | Molecular vibrational signals used to match a material against a reference library. | Rapid screening of many solid or liquid samples; some instruments can analyze through suitable transparent packaging. | Often requires little or no sample preparation; can provide an on-site material identification result. | Fluorescence, dark or mixed samples, packaging, and substances absent from the library can affect results. A match is not a universal guarantee of purity or composition. | Fast, non-destructive screening of accessible samples where the library covers the substances of interest. |
| Handheld FTIR spectroscopy | Infrared absorption patterns associated with chemical bonds in a sample. | Contact analysis of a small portion of a solid, powder, or liquid, depending on the instrument and sampling accessory. | Can distinguish many compounds using their infrared spectra and generally does not require a complex laboratory setup. | Usually needs direct access to the sample. Mixtures, low-concentration components, and poor contact can make interpretation more difficult. | On-site screening when a representative sample can be safely collected and placed on the analyzer. |
| Ion mobility spectrometry (IMS) | The movement of ionized molecules through a gas under an electric field; many systems are configured to detect targeted trace compounds. | Trace-residue screening, often using a swab or sampled air. | Designed for rapid trace detection and can be useful when visible bulk material is unavailable. | Results depend on target settings, sampling, and potential interferences. A trace alarm does not by itself establish the identity, amount, or source of a bulk substance. | Screening surfaces, packages, or locations for residues of substances included in the system’s target list. |
| Portable mass spectrometry | Mass-to-charge patterns of ions generated from a sample, interpreted using analytical methods and reference data. | Field analysis where more detailed chemical information is needed and trained operators can manage sampling and instrument procedures. | Can provide detailed chemical evidence and may help distinguish compounds that simpler screening methods cannot separate. | Typically more demanding in cost, training, sample handling, and maintenance than basic screening tools; capabilities vary by instrument and method. | Specialist field teams needing richer analytical information than a basic screening result provides. |
| Colorimetric presumptive test | A visible color change caused by a chemical reaction with certain substances or substance classes. | A preliminary spot test using a small sample and a reagent kit. | Simple and portable; useful for an initial screening decision when used according to its instructions. | Usually presumptive rather than definitive. Similar reactions, mixtures, sample condition, and user interpretation can affect the result; reagents also require safe handling. | Low-complexity preliminary screening, not confirmatory identification. |